Research Technologist I

Position Description:

Purpose

Research technician position is available in the Department of Cell Biology focused on biochemistry and drug discovery for G protein-coupled receptors (GPCRs), which are major drug targets for medicine. Our lab is a highly-creative and and dynamic Cell Biology lab involved in cutting-edge technologies collaborating internationally on projects with other labs. We specialize in pharmacology and using protein structure to design and screen compounds as potential drugs at various GPCR signaling pathways aimed at treating depression, pain, cancer, and various other diseases.

Technicians work in a team environment and collaborate on several projects and develop techniques/skill sets including but not limited to: molecular biology/DNA construct design, tissue culture and protein expression, high-throughput screening and drug discovery, quantitative pharmacology and structure-activity relationships, mutagenesis and chemical biology, and protein purification and structural/biophysical methods of measurement. Technicians also co-publish on high-impact discoveries from the lab and have opportunity to develop their own projects.

We welcome highly-motivated and well-organzied candidates capable of independent work in a laboratory setting. Candidates should have strong interests in medicine and/or pharmacology with strong backgrounds in biochemistry or biology related fields of study. Candidates with some experience with tissue culture/aseptic techniques (e.g. HEK, CHO cells), protein expression and/or purification (e.g. SDS-PAGE, Western blot), or molecular biology (e.g. PCR, primer design) are desired.

Primary Functions

• Demonstrate attention to detail, good organizational and time management skills
• Perform daily tissue culture and maintenace of cell lines
• Perform weekly protein expression and/or purification procedures
• Prepare weekly buffers, dilutions, or stock solutions for routine procedures and cell culture treatments
• Perform weekly experiments, data analysis, and data archiving according to supervisors' specifications
• Attend weekly individual meetings with supervisors and lab meetings/journal clubs with the group
• Operate and help maintain analytical and high-throughput equipment for protein quality control analysis (e.g. HPLC, SDS-PAGE) and cell signaling (e.g. fluorescence and luminescence assays)
• Monthly inventory of supplies and routine monitoring of lab reagents/supplies
• Daily to weekly ordering of reagents and supplies
• Maintain detailed and accurate data records in notebooks for all performed assays
• Work in a team environment to help others and train other lab members

Knowledge - Skills - Abilities

Knowledge of biochemistry or molecular biology is required.

A highly organized individual with stellar record management skills is required.

Excellent written and verbal communication skills are required.

Tissue culture/aseptic techniques, molecular biology, or protein biochemistry skills are strongly recommended.

Preferred Schedule:



Full Time/Variable

Position Requirements:

Specifications

Appropriate experience may be substituted on equivalent basis

Minimum Required Education: Bachelor's degree in scientific field

Preferred Education: Biochemistry, Biology or related field

Preferred Experience: Tissue Culture, Molecular Biology, or Protein Biochemistry Techniques

Field: Biochemistry and/or Biology

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MCW as an Equal Opportunity Employer and Commitment to Non-Discrimination


The Medical College of Wisconsin (MCW) is an Equal Opportunity Employer. We are committed to fostering a diverse community of outstanding faculty, staff, and students, as well as ensuring equal educational opportunity, employment, and access to services, programs, and activities, without regard to an individual's race, color, national origin, religion, age, disability, sex, gender identity/expression, sexual orientation, marital status, pregnancy, predisposing genetic characteristic, or military status. Employees, students, applicants or other members of the MCW community (including but not limited to vendors, visitors, and guests) may not be subjected to harassment that is prohibited by law or treated adversely or retaliated against based upon a protected characteristic.

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