Senior Research Scientist

Position Summary

Dr. Chai's lab in the Center for Genetic Diseases in the Chicago Medical School at Rosalind Franklin University of Medicine and Science welcome applications for a full-time Senior Research Scientist to conduct scientific research. We are seeking an experienced researcher to conduct original research using human cell lines and mice to study the role of genome instability and replication stress in carcinogenesis, and how to target genome maintenance to improve cancer treatment.

Who We Are

We are a highly interactive team using integrated genomics, molecular/cell biology, and in vivo approaches to advance targeted cancer therapy. Additional information regarding the Chai Lab can be found at: https://weihangchai.wixsite.com/chailab

Essential Duties & Responsibilities

• Conduct original research to understand the molecular mechanism for maintaining genome stability in cells and the role of replication stress in carcinogenesis.
• Independently perform research activities and data analysis.
• Independently draft manuscripts and prepare figures for publications and grant proposals.
• Assist PI in preparing grant applications.
• Attend research conferences and present research findings at conferences. Travel (<5%) may be needed.
• Maintain and ensure compliance with regulatory protocols and records.

Conditions of Employment

• Must achieve satisfactory results from a background check
• Compliance with the current COVID19 vaccination policy

Required Education & Experience

Ph.D. in biochemistry, cell or molecular biology, or other discipline related to the molecular biosciences, with 6+ years of post-PhD research experience in academia. Demonstrated expertise in molecular/cell biology. Record indicating outstanding abilities and potential in research; and a publication record with first-authorship in reputable journals consistent with years of training and background. Strong communication skills, both orally and written.

Required Knowledge, Skills, & Abilities

Strong skills in Molecular and Cell Biology: Cell culture, Animal handling, Western blotting, molecular cloning/subcloning, immunofluorescence microscopy, flow cytometry, co-immunoprecipitation, RNAi, CRISPR-Cas9 to make knockout or knockin, Nucleic Acid isolation, agarose and polyacrylamide gel electrophoresis, molecular cloning, restriction digestion, working with retrovirus and lentivirus, PCR, qPCR, RT-PCR, Protein analysis, experience with immune function analysis, etc.

Statistical analysis, ability to use GraphPad Prism, EndNote, BioRender, Microsoft Office including Word, Powerpoint, Blast analysis, Primer design, etc.

Preferred Qualifications

Prior experience with immune function analysis and solid tumor analysis in vivo is preferred. Experience with NIH grant preparation is preferred.

Typical Physical Demands & Working Conditions

• Selected candidate must have the mental and physical capabilities to perform the essential functions of the position with or without reasonable accommodations.

EOE, Including Disability / Vets