Research Scientist, Department of Cancer Biology, College of Medicine
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![]() United States, Ohio, Cincinnati | |
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Research Scientist, Department of Cancer Biology, College of Medicine Current UC employees must apply internally via SuccessFactors Founded in 1819, the University of Cincinnati ranks among the nation's best urban public research universities. Home to 53,235 students, nearly 12,000 faculty and staff and 350,000+ living alumni, UC combines a Top 35 public research university with a physical setting The New York Times has called "the most ambitious campus design program in the country." With the launch of Next Lives Here, the Cincinnati Innovation District, a $100 million JobsOhio investment, the oldest and one of the largest cooperative education programs, a dynamic academic health center and entry into the Big 12 Conference, UC's momentum has never been stronger. UC's annual budget stands at $1.85 billion, and its endowment totals $2 billion. UC is a mission-driven organization where we are committed to student success and positively transforming the community through scholarship and service. We thrive on innovation, making an impact, and fostering an environment where staff and faculty are key contributors to UC's success. Job Overview
A Research Scientist position is available in the laboratory of Dr. Xiaoting Zhang in the Department of Cancer Biology at the University of Cincinnati College of Medicine, to study transcriptional and epigenetic gene regulation in breast cancer metastasis and therapeutic resistance. The Zhang laboratory (https://med.uc.edu/zhanglab) currently focuses on elucidating the role and molecular mechanisms of gene- and tissue-specific transcriptional cofactors, small RNAs and liquid-liquid phase separation (LLPS) in the above processes [Estrogen Receptor and Breast Cancer - Celebrating the 60thAnniversary of the Discovery of ER (1sted, 2019, Springer Nature),Dev Cell (2021)56(3):341,Cell Reports (2021) 34(10):108822,Cancer Drug Resist2022; 5(2): 498,Autophagy(2023)19(6):1662, Cancers (2024) 16(23):3992]. We are using a combination of biochemical, molecular, genomic, and mouse genetic (conditional knockout, mutant knockin, and overexpression) approaches. We are also currently developing RNA-based nano-therapeutics to target these cofactors and small RNAs to overcome the therapeutic resistance of human breast cancer. Essential Functions
Required Education
PhD and/or MD required. Required Experience
Additional related work experience may be required depending on field or discipline. Additional Qualifications Considered
Prior experience and in-depth knowledge in cancer biology, molecular cellular biology, protein biochemistry, small RNAs, or LLPS is ideal. Physical Requirements/Work Environment
Compensation and Benefits UC offers an exceptional benefits package designed to support your well-being, financial security, and work-life balance. (UC Benefits Link) Highlights include: Comprehensive Tuition Remission UC provides tuition remission for you and your eligible dependents, covering tuition costs for nearly all undergraduate and graduate programs offered by the university. Robust Retirement Plans As a UC employee, you won't contribute to Social Security (except Medicare). Instead, you'll choose between state pension plans (OPERS, STRS) or an Alternative Retirement Plan (ARP), with UC contributing 14-18% of your salary based on position. Real Work-Life Balance UC prioritizes work-life balance with a generous time-off policy, including: Vacation and sick time 11 paid holidays and additional end-of-year paid time off (Winter Season Days) 6 weeks of paid parental leave for new parents Additional Benefits Include:
To learn more about why UC is a great place to work, please visit our careers page athttps://www.uc.edu/careers.html UC is an E-Verify employer. If hired into this position, you will be required to provide satisfactory proof of employment eligibility by providing acceptable, original forms of identification for employment verification via the Federal I-9 employment verification process. A list of acceptable documents can be seen here:https://www.uscis.gov/i-9-central/form-i-9-acceptable-documents Important: To apply you must create a profile and submit a complete job application through the UC applicant portal. We are unable to consider "easy apply" applications submitted via other websites. For questions about the UC recruiting process or to request accommodations with the application, please contact Human Resources atjobs@uc.edu. The University of Cincinnati is an Equal Opportunity Employer. REQ:98991 SF:OMJ SF:RM SF:HEJ, SF:INS SF:HERC SF:DIV SF:LJN SF:IHE Research Scientist, Department of Cancer Biology, College of Medicine Date: May 12, 2025 Location: Cincinnati, OH, US Facility: Main Campus
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