New

Research Technician

California Institute of Technology
vision insurance, parental leave, paid time off, sick time, tuition reimbursement
United States, California, Pasadena
Oct 23, 2025
Caltech is a world-renowned science and engineering institute that marshals some of the world's brightest minds and most innovative tools to address fundamental scientific questions. We thrive on finding and cultivating talented people who are passionate about what they do. Join us and be a part of the diverse Caltech community. Job Summary To meet the growing needs of the Mayo Laboratory in the Division of Biology and Biological Engineering, we are looking for a passionate and skilled Research Technician to join our team. The successful candidate will assist a multidisciplinary research team to study protein engineering strategies for extracellular vesicle formation as part of a larger effort to develop novel therapies for autoimmune diseases. Essential Job Duties Molecular biology tasks, including cloning (PCR, gel electrophoresis, sequencing, and validating constructs, etc.) and plasmid preparation. Protein purification (affinity and size exclusion chromatography). Western blotting and SDS-PAGE. Bioconjugations of proteins, ELISAs, and other assays. Transfection and maintenance of mammalian cell lines. General lab duties, including buffer and reagent prep. Maintaining records. Other duties as assigned. Work on weekends is included in the regular 5-day work week. Basic Qualifications BA or BS in Biology or related field. At least one year of experience in a biology or chemistry research laboratory. Mammalian cell culture experience. Protein purification experience. Knowledge of buffer prep and calculations. Excellent communication skills (oral and written). Ability to work in a team environment. Ability to work on weekends. Preferred Qualifications Background in immunology, molecular biology, or structural biology. BSL-2 experience. Transfection and maintenance of mammalian or yeast cell lines. Previous experience working with mice or other murine animal models. Experience collecting and processing diagnostic samples. Experience receiving and feeding animals. Experience administering drugs and other treatments. Animal husbandry experience. Experience performing daily health observations and completing reports. Required Documents Resume or CV Cover Letter Hiring Range $25.25 - $30.75 Per Hour The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, internal equity, experience, education, specialty and training. As one of the largest employers in Pasadena, CA, Caltech is committed to providing comprehensive benefits to eligible employees and their eligible dependents. Our benefits package includes competitive compensation, health, dental, and vision insurance, retirement savings plans, generous paid time off (vacation, holidays, sick time, parental leave, bereavement, etc.), tuition reimbursement, and more. Non-benefit eligible employees will have access to some benefits such as onsite counseling and sick time. Learn more about our benefits and staff perks. EEO Statement We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity, or national origin, disability status, protected veteran status, or any other characteristic protected by law. Caltech is a VEVRAA Federal Contractor. To read more Equal Employment Opportunity (EEO) go to eeoc_self_print_poster.pdf. Disability Accommodations Caltech complies with the Fair Employment and Housing Act (FEHA) and the Americans with Disabilities Act (ADA). We consider reasonable accommodation measures that may be necessary for eligible applicants and employees to perform the essential functions of a position. If you would like to request an accommodation to complete this application, interview, or otherwise participate in the employee selection process, please contact Caltech Recruiting at employment@caltech.edu. Additionally, if you do not meet the basic qualifications of a role but believe you can perform the essential functions of the job with reasonable accommodation, please reach out to Caltech Recruiting at employment@caltech.edu.