New

Molecular Dynamics Simulation Specialist

The Pennsylvania State University
remote work
United States, Pennsylvania, University Park
201 Old Main (Show on map)
Nov 13, 2025
APPLICATION INSTRUCTIONS: CURRENT PENN STATE EMPLOYEE (faculty, staff, technical service, or student), please login to Workday to complete the internal application process. Please do not apply here, apply internally through Workday. CURRENT PENN STATE STUDENT (not employed previously at the university) and seeking employment with Penn State, please login to Workday to complete the student application process. Please do not apply here, apply internally through Workday. If you are NOT a current employee or student, please click "Apply" and complete the application process for external applicants. Approval of remote and hybrid work is not guaranteed regardless of work location.For additional information on remote work at Penn State, seeNotice to Out of State Applicants. JOB DESCRIPTION AND POSITION REQUIREMENTS Job Title: Molecular Dynamics Simulation Specialist Position Type: Wage Payroll Location: 8 Althouse Lab, Pennsylvania State University Position Summary: We are seeking a highly skilled molecular biologistwith strong expertise in molecular dynamics (MD) simulationsto support computational studies on coronavirus replication machinery. The successful candidate will contribute to ongoing research focused on the polymerase, helicase, and exoribonuclease subcomplexesof coronavirus replication complexes, with the goal of understanding molecular mechanisms and identifying potential antiviral targets. Responsibilities: Perform and analyze molecular dynamics simulationsof viral protein complexes, including polymerase, helicase, and exoribonuclease assemblies. Collaborate with experimental and computational researchers to integrate MD data with biochemical and structural findings. Prepare detailed reports, visualizations, and summaries of simulation outcomes. Contribute to manuscript preparation and presentations. Maintain accurate computational records and ensure reproducibility of analyses. Required Qualifications: Ph.D. degree in Molecular Biology, Biochemistry, Biophysics, Computational Biology, or a related field. Demonstrated experience in molecular dynamics simulationsusing packages such as GROMACS, AMBER, NAMD, or CHARMM. Strong understanding of protein structure, enzyme mechanisms, and biomolecular interactions. Experience with Linux/Unix environments, scripting (Python, Bash), and data analysis tools. Excellent written and verbal communication skills and ability to work in a collaborative research environment. Preferred Qualifications: Experience working with viral replication proteinsor nucleic acid-processing enzymes. Demonstrated publications. Familiarity with high-performance computing (HPC)environments and cluster job management systems. Knowledge of homology modeling, docking, or free energy calculations. Appointment Details: Duration: 15 hours/week for 28 weeks Application Instructions: Please submit a CV, a brief cover letterdescribing relevant experience. BACKGROUND CHECKS/CLEARANCES Employment with the University will require successful completion of background check(s) in accordance with University policies. CAMPUS SECURITY CRIME STATISTICS Pursuant to the Jeanne Clery Disclosure of Campus Security Policy and Campus Crime Statistics Act and the Pennsylvania Act of 1988, Penn State publishes a combined Annual Security and Annual Fire Safety Report (ASR). The ASR includes crime statistics and institutional policies concerning campus security, such as those concerning alcohol and drug use, crime prevention, the reporting of crimes, sexual assault, and other matters. The ASR is available for review here. EEO IS THE LAW Penn State is an equal opportunity employer and is committed to providing employment opportunities to all qualified applicants without regard to race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. If you are unable to use our online application process due to an impairment or disability, please contact 814-865-1473. The Pennsylvania State University is committed to and accountable for advancing equity, respect, and belonging. We embrace individual uniqueness, as well as a culture of belonging that supports equity initiatives, leverages the educational and institutional benefits of inclusion in society, and provides opportunities for engagement intended to help all members of the community thrive. We value belonging as a core strength and an essential element of the university's teaching, research, and service mission. Federal Contractors Labor Law Poster PA State Labor Law Poster Penn State Policies Copyright Information Hotlines