POSTDOCTORAL ASSOCIATE

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Job Description:

A grant funded postdoctoral position is immediately available in the Department of Neurosurgery at the Duke University School of Medicine. The position will be jointly mentored by Drs Quinn Ostrom (Assistant Professor of Neurosurgery and Population Health Sciences) and Anoop Patel (Associate Professor of Neurosurgery, Biomedical Engineering, and Pathology. The Ostrom lab is focused on understanding genetic and other factors which influence susceptibility to and prognosis of primary brain tumors. The Patel lab is focused on using single-cell sequencing techniques to study intratumoral heterogeneity in malignant brain tumors.

The primary responsibilities for this position will be focused on analysis of single-cell transcriptomic and epigenomic datasets with the goal of identifying cell types that modulate GBM predisposition. The candidate will also have the opportunity to conceptualize, design, and lead independent research projects aligned with their interests and the broader goals of the project under Drs Ostrom and Patel's mentorship.

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Requirements:

The applicant should have a Ph.D. in computational biology, bioinformatics, computer science, statistics, genetic epidemiology, or a related field. Expertise in analysis of single cell or spatial sequencing data is required. Experience in analysis of bulk RNA and whole exome sequencing data, and genotyping array data is preferred but not required. Experience in the generation of single cell sequencing data including preparation of high quality single cell/nucleus suspensions from patient tissue, running droplet based microfluidic platforms (10X Genomics), and next generation sequencing library preparation are preferred but not required.

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How to apply:

Please submit a cover letter describing your prior research experience and interests, your future research and career goals, and an expected starting date. Additionally, please submit a current CV and that name of three references.