Bioinformatics Engineer (Hybrid)

Pay Range: $95,000.00 - $125,000.00 / year

Salary offers are based on a wide range of factors including relevant skills, training, experience, education, and, where applicable, certifications obtained. Market and organizational factors are also considered. Successful candidates may be eligible to receive annual performance bonus compensation.

Benefits Information:

We are proud to offer best-in-class benefits and programs to support employees and their families in living healthy, happy lives. Our pay and benefit plans have been designed to promote employee health in all respects - physical, financial, and developmental. Depending on whether it is a part-time or full-time position, some of the benefits offered may include:

* Day 1 Medical, supplemental health, dental & vision for FT employees who work 30+ hours

* Best-in-class well-being programs

* Annual, no-cost health assessment program Blueprint for Wellness

* healthyMINDS mental health program

* Vacation and Health/Flex Time

* 6 Holidays plus 1 "MyDay" off

* FinFit financial coaching and services

* 401(k) pre-tax and/or Roth IRA with company match up to 5% after 12 months of service

* Employee stock purchase plan

* Life and disability insurance, plus buy-up option

* Flexible Spending Accounts

* Annual incentive plans

* Matching gifts program

* Education assistance through MyQuest for Education

* Career advancement opportunities

* and so much more!

About Haystack Oncology

Haystack Oncology, now part of Quest Diagnostics, is a next-generation liquid biopsy company focused on advancingtumor-informed minimal residual disease (MRD) testing. Our proprietary technology enables highly sensitive and specific detection of circulating tumor DNA (ctDNA), improving patient outcomes through earlier detection of residual disease.

As we continue to expand ourassay portfolio and bringcutting-edge diagnostics to the public, we are seeking a skilledBioinformatics Scientist to join our growing team. This role will play a critical part in supportingclinical production testing, clinical trials, and assay R&D for Quest Diagnostics laboratories in the US and Europe.

Role Overview

As aBioinformatics Scientist, you will develop and maintaincloud-based computational infrastructure for the analysis of genomic data from our proprietary MRD assays. You will work cross-functionally withlaboratory, LIMS, and IT teams to ensure seamless integration of bioinformatics workflows with clinical and research operations.

• Develop & maintain cloud infrastructure for scalable and efficient genomic data analysis.

• Implement and optimize Python and Nextflow bioinformatics workflows.

• Integrate bioinformatics pipelines with Laboratory Information Management Systems (LIMS) to streamline data processing.

• Ensure compliance with IT security and privacy controls, aligning with Quest Diagnostics' corporate policies.

• Apply software engineering best practices, contributing to thescalability, robustness, and maintainability of bioinformatics pipelines.

• Develop and manage databases and applications forquality control (QC) and assay performance monitoring.

• Document and validate bioinformatics systems in compliance with regulatory and quality standards for clinical diagnostics

Required:

• Background in software or infrastructure engineering, with experience inbioinformatics.

• Proficiency inbioinformatics pipeline workflow management, particularlyNextflow (preferred), Cromwell, or CWL.

• Hands-on experience developingcloud-native infrastructure (AWS preferred) forstorage, batch computing, and serverless applications.

• Expertise ininfrastructure as code (IaC) technologies such as Terraform or AWS CDK.

• Strong programming skills inPython, JavaScript/TypeScript, R, or other relevant scripting languages.

• Experience withAPI development and integration, particularly JSON-basedRESTful APIs.

• Deep understanding ofversion control (Git), CI/CD best practices, and software development lifecycle (SDLC).

• Ability to workcross-functionally in a multi-disciplinary environment with minimal supervision.

• Strong problem-solving, analytical, and troubleshooting skills, with the ability to diagnose and resolve technical issues.

• Excellent verbal and written communication skills in English, with the ability to translate technical concepts for non-technical stakeholders.

Preferred:

• Experience in a clinical diagnostics or regulated environment (e.g., CLIA, CAP, IVDR, FDA) with knowledge of software validation and regulatory requirements.

• Understanding ofcontrolled processes, environment management, and quality control systems in a clinical setting.

• Familiarity withDevOps methodologies.

Education:

• Bachelor's Degree (Required)

• Master's Degree (Preferred