Postdoctoral Fellow in Cellular Pharmacology - Biological Sciences - Jeff Skolnick

Georgia Tech prides itself on its technological resources, collaborations, high-quality student body, and its commitment to building an outstanding and diverse community of learning, discovery, and creation. We strongly encourage applicants whose values align with our institutional values, as outlined in our strategic plan. These values include academic excellence, diversity of thought and experience, inquiry and innovation, collaboration and community, and ethical behavior and stewardship. Georgia Tech has policies to promote a healthy work-life balance and is aware that attracting faculty may require meeting the needs of two careers.

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Georgia Tech is a top-ranked public research university situated in the heart of Atlanta, a diverse and vibrant city with numerous economic and cultural strengths. The Institute serves more than 45,000 students through top-ranked undergraduate, graduate, and executive programs in engineering, computing, science, business, design, and liberal arts. Georgia Tech's faculty attracted more than $1.4 billion in research awards this past year in fields ranging from biomedical technology to artificial intelligence, energy, sustainability, semiconductors, neuroscience, and national security. Georgia Tech ranks among the nation's top 20 universities for research and development spending and No. 1 among institutions without a medical school.

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About the School of Biological Sciences at the Georgia Institute of Technology

Undergraduate degree programs include 4-year BS and 5-year BS/MS programs in Biology and Bioinformatics. Graduate degree programs include MS and PhD in Biology, MS and PhD in Bioinformatics, MS and PhD in Computational Science and Engineering as well as PhD in Quantitative Biosciences, Ocean Sciences and Engineering, Applied Physiology, and Dual Degree Doctor of Physical Therapy/ Doctor of Philosophy. Research strengths include Computational Biology and Bioinformatics, Ecology, Evolution, Integrative Physiology, Microbial Dynamics and Infection, Neuroscience, Molecular and Cell Biology, Molecular Biomedical Sciences.The school is home to the two largest and most distinctive undergraduate majors in the College of Sciences: Biology and Neuroscience. Faculty members in the School of Biological Sciences have the opportunity to work with students from all majors on campus.

Postdoctoral Fellow in Protein Biochemistry and Assay Development in the Skolnick Group in the School of Biological Sciences at Georgia Tech

Seeking an experienced in vitro cellular pharmacologist with expertise in advanced cellular assay systems to support mechanistic studies of target biology, metabolite target interaction and compound activity. The successful candidate will have hands-on experience with 2D cellular models(some experience with and 3D culture including spheroids and organoids is desirable), as well as functional and target engagement assays. The candidate will be highly motivated, be a self-starter, and be able to independently design and execute experiments, interpret complex data, and work effectively in a multidisciplinary research environment.

Responsibilities Include:

Design and execute mechanistic in vitro cellular studies to investigate target biology and evaluate compound activity.

Develop, optimize, and apply advanced cellular assay systems using 2D cell models (some exposure into 3D models, including spheroids and organoids, is desirable).

Perform functional assays, including proliferation, viability, dose-response, and washout/recovery studies.

Develop and implement target engagement assays, including NanoBRET and NanoBiT approaches, to characterize proteinprotein and proteinsmall molecule interactions.

Engineer cellular models and signaling pathways using modern molecular biology techniques.

Generate, validate, maintain, cryopreserve, and catalogue stable cell lines for research applications.

Prepare cell culture media, reagents, growth factors, compounds, and other materials required for experimental studies.

Independently troubleshoot complex experimental and technical challenges and implement appropriate solutions.

Collect, analyze, interpret, and document quantitative experimental data using appropriate analytical and statistical methods.

Maintain complete, accurate, and reproducible electronic records of experimental procedures, results, and data analyses.

Develop, update, and maintain detailed protocols and standard operating procedures for cellular assays and laboratory processes.

Contribute biological and experimental expertise to project planning, study design, and research strategy.

Collaborate with computational scientists, chemists, biologists, and other multidisciplinary team members to advance research programs.

Communicate complex scientific findings clearly through written reports, presentations, publications, and discussions with internal and external stakeholders.

Present research findings at project meetings, scientific conferences, and other professional forums.

Contribute to manuscripts, abstracts, posters, and other scientific publications and presentations.

Maintain cell culture instrumentation and laboratory equipment, including routine cleaning, calibration coordination, contamination monitoring, and CO supply checks.

Assist with laboratory operations, including inventory management, procurement of supplies, obtaining quotes, and tracking reagents and consumables.

Monitor scientific and technical developments relevant to advanced cellular models, target engagement, and compound evaluation.

Take ownership of assigned research programs, manage experimental priorities, and meet project timelines in a fast-paced research environment.

Attend required meetings and participate in team, laboratory, and professional development activities.

Communicate effectively both orally and in writing and demonstrate scientific rigor, initiative, collaboration, and a strong sense of timeliness.

PhD in Biochemistry, Biophysics, Enzymology, Chemical Biology, or a related discipline.

Strong hands-on experience in recombinant protein production, enzymology, assay development, and biophysical characterization.

Excellent problem-solving, data analysis, organizational, and communication skills.

Ability to work independently while contributing effectively within interdisciplinary teams.

Applicants should upload a single PDF, which should include:

Cover letter stating your interest in this position.

Your fit and previous experience related to this position description, including scientific goals and interests.

CV.

Names and contact information for three persons willing to provide a recommendation.

The University System of Georgia is comprised of our 25 institutions of higher education and learning as well as the System Office. Our USG Statement of Core Values are Integrity, Excellence, Accountability, and Respect. These values serve as the foundation for all that we do as an organization, and each USG community member is responsible for demonstrating and upholding these standards. More details on the USG Statement of Core Values and Code of Conduct are available in USG Board Policy 8.2.18.1.2 and can be found on-line at https://www.usg.edu/policymanual/section8/C224/#p8.2.18_personnel_conduct.

Additionally, USG supports Freedom of Expression as stated in Board Policy 6.5 Freedom of Expression and Academic Freedom found on-line at https://www.usg.edu/policymanual/section6/C2653.

The Georgia Institute of Technology (Georgia Tech) is an Equal Employment Opportunity Employer. The Institute is committed to maintaining a fair and respectful environment for all. To that end, and in accordance with federal and state law, Board of Regents policy, and Institute policy, Georgia Tech provides equal opportunity to all faculty, staff, students, and all other members of the Georgia Tech community, including applicants for admission and/or employment, contractors, volunteers, and participants in institutional programs, activities, or services. Georgia Tech complies with all applicable laws and regulations governing equal opportunity in the workplace and in educational activities.

Equal opportunity and decisions based on merit are fundamental values of the University System of Georgia ("USG") and Georgia Tech. Georgia Tech prohibits discrimination, including discriminatory harassment, on the basis of an individual's race, ethnicity, ancestry, color, religion, sex (including pregnancy), national origin, age, disability, genetics, or veteran status in its programs, activities, employment, and admissions. Further, Georgia Tech prohibits citizenship status, immigration status, and national origin discrimination in hiring, firing, and recruitment, except where such restrictions are required in order to comply with law, regulation, executive order, or Attorney General directive, or where they are required by Federal, State, or local government contract.

A successful candidate must be able to pass a background check. Please visit: https://usg.policystat.com/policy/19298143/latest