Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 11 - 20 of 95 |
Senior Manager, Quality, Standards and Compliance
Cambridge, Massachusetts
Overview The Senior Manager, Quality Standards and Compliance (QSC) is responsible for developing and maintaining the Regulatory Sciences compliance framework and providing oversight of compliance-related activities across Regulatory Strate...
13h
| Job Type | Full Time |
Norton, Massachusetts
Overview The Senior Manager, Manufacturing Operations is an integral part of the Norton Internal Manufacturing team. This role will initially be involved in the start-up of Norton's new commercial Drug Substance manufacturing train, includi...
13h
| Job Type | Full Time |
Senior Manager, Commercial Training and Development
Cambridge, Massachusetts
Overview: The Senior Manager, US Commercial Training & Development - TTR Franchise reports to the Associate Director. This role involves developing and implementing capability building strategies, plans and processes that drive measurable f...
13h
| Job Type | Full Time |
Senior Manager, Clinical Data Management
Cambridge, Massachusetts
Senior Manager, Clinical Data Management The Senior Manager, Clinical Data Management will lead and contribute to data management activities in support of Alnylam studies across all stages of clinical drug development. Summary of Key Respon...
13h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: The Senior Director, Pathology will provide scientific leadership for the interpretation and application of clinical pathology data across Alnylam's research and development portfolio. This individual will serve as a key subject m...
13h
| Job Type | Full Time |
Senior Director, Head of PV Science
Philadelphia, Pennsylvania
Overview Alnylam is the industry leader in the translation of RNA interference (RNAi) into a new class of innovative medicines with the potential to address the unmet needs of patients with debilitating diseases. Founded in 2002, Alnylam wa...
13h
| Job Type | Full Time |
Senior Director, Head of PV Science
Cambridge, Massachusetts
Overview Alnylam is the industry leader in the translation of RNA interference (RNAi) into a new class of innovative medicines with the potential to address the unmet needs of patients with debilitating diseases. Founded in 2002, Alnylam wa...
13h
| Job Type | Full Time |
Senior Director, Clinical Research - Neurodegeneration
Cambridge, Massachusetts
Overview Alnylam Pharmaceuticals is seeking an imaginative physician drug developer. This is an opportunity to provide clinical leadership in developing RNAi therapeutics in Alnylam's rapidly expanding portfolio, which spans the areas of ra...
13h
| Job Type | Full Time |
Senior Director, Clinical Research - Neurodegeneration
Cambridge, Massachusetts
Overview Alnylam Pharmaceuticals is seeking an imaginative physician drug developer. This is an opportunity to provide clinical leadership in developing RNAi therapeutics in Alnylam's rapidly expanding portfolio, which spans the areas of ra...
13h
| Job Type | Full Time |
Senior Director Biostatistics Head of Statistical Innovation & Methodology
Philadelphia, Pennsylvania
Senior Director Biostatistics, Head of Statistical Innovation & Methodology Overview At Alnylam, the Senior Director Biostatistics, Head of Statistical Innovation & Methodology will provide scientific leadership in advanced statistical meth...
13h
| Job Type | Full Time |