Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 114 |
Senior Director, US Strategic Accounts
Cambridge, Massachusetts
Overview The Senior Director, US Strategic Accounts provides strategic leadership for Alnylam's Strategic Accounts Management organization, overseeing the strategy, development, and execution of account plans across priority health systems ...
4h
| Job Type | Full Time |
Norton, Massachusetts
Overview: Under minimal supervision and with limited guidance, this individual will manufacture GMP products in Train 1 at the Norton Manufacturing Facility, ensuring safe, efficient and cGMP-compliant operations at all times. Responsibilit...
4h
| Job Type | Full Time |
Field Reimbursement Manager - Great Lakes North
Minneapolis, Minnesota
Overview: The Field Reimbursement Manager (FRM) serves as the access and coverage subject matter expert for Alnylam products. The FRM educates healthcare providers (HCPs) and office staff on reimbursement processes, payer requirements, cove...
4h
| Job Type | Full Time |
Associate Scientist II - Delivery Biology
Cambridge, Massachusetts
Overview: We are seeking a highly motivated Associate Scientist II in Delivery Biology to support our efforts focused on improving the cellular delivery of nucleic acid-based therapeutics. The successful candidate will play a key part in ge...
4h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview The Associate Director of Marketing, KOL Engagement and Enablement is responsible for leading strategic initiatives that enhance Key Opinion Leader (KOL) engagement, Thought Leader Liaison (TLL) effectiveness, and the optimization ...
4h
| Job Type | Full Time |
Sr. Director, HCP TTR Marketing
Cambridge, Massachusetts
Overview The Senior Director, HCP Marketing, US TTR, will lead HCP marketing strategy and execution across AMVUTTRA (vutrisiran), ONPATTRO (patisiran), and TTR disease education. This leader will oversee branded marketing, digital and non-p...
13h
| Job Type | Full Time |
Sr. Manager, Clinical Operations
Cambridge, Massachusetts
The Sr. Manager, Clinical Operations is responsible for leading the operational planning and execution of global clinical trials from study start-up through closeout. This role provides leadership to cross-functional trial teams, ensuring t...
1d
| Job Type | Full Time |
Cambridge, Massachusetts
Overview The Early Development and Research Departments at Alnylam are seeking a Lab Operations Associate to join our team to support the Sample Management group in the receiving and storage of clinical and nonclinical samples. We are seeki...
1d
| Job Type | Full Time |
Director, Global Market Access
Cambridge, Massachusetts
Overview: Reporting to the VP, Global Market Access, the candidate will act as the overall lead for global pricing & market access strategy for Alnylam's Rare Disease portfolio, as well as for selected pipeline assets, bringing key learning...
4d
| Job Type | Full Time |
Associate Director, Commercial Consent, Identity & Preference Management
Cambridge, Massachusetts
Overview: Alnylam is seeking an experienced and highly collaborative Associate Director, Commercial Consent, Identity & Preference Management to lead the Commercial business capability needed to capture, manage and honor consent, identity a...
4d
| Job Type | Full Time |